Lecture Notes in Computer Science vol:3565 pages:689-700
Information processing in medical imaging - IPMI 2005 location:Glenwood Springs, CO, USA date:11-15 July 2005
In this paper, we evaluate different schemes for constructing a mean shape anatomical atlas for atlas-based segmentation of MR brain images. Each atlas is constructed and validated using a database of 20 images for which detailed manual delineations of 49 different subcortical structures are available. Atlas construction and atlas based segmentation are performed by non-rigid intensity-based registration using a viscous fluid deformation model with parameters that were optimally tuned for this particular task. The segmentation performance of each atlas scheme is evaluated on the same database using a leave-one-out approach and measured by the volume overlap of corresponding regions in the ground-truth manual segmentation and the warped atlas label image.
Wang Q., Seghers D., D’Agostino E., Maes F., Vandermeulen D., Suetens P., Hammers A., ''Construction and validation of mean shape atlas templates for atlas-based brain image segmentation'', Lecture notes in computer science, vol. 3565, pp. 689-700, 2005 (Proceedings information processing in medical imaging - IPMI 2005, July 11-15, 2005, Glenwood Springs, Colorado, USA).