Lecture Notes in Computer Science vol:4057 pages:206-213
3rd International Workshop on Biomedical Image Registration location:Utrecht, The Netherlands date:July 9-11, 2006
Because of its robustness and accuracy for a variety of applications, either monomodal or multimodal, mutual information (MI) is a very popular similarity measure for (medical) image registration. Calculation of MI is based on the joint histogram of the two images to be registered, expressing the statistical relationship between image intensities at corresponding positions. However, the calculation of the joint histogram is not straightforward. The discrete nature of digital images, sampled as well in the intensity as in the spatial domain, impedes the exact calculation of the joint histogram. Moreover, during registration often an intensity will be sought at a non grid position of the floating image.