Polypropylenimine dendrimers: Improved synthesis and characterization
deBrabander, EMM × Brackman, J MureMak, M De Man, Hugo Hogeweg, M Keulen, J Scherrenberg, R Coussens, B Mengerink, Y vanderWal, S #
Huthig & wepf verlag
Macromolecular symposia vol:102 pages:9-17
Both the Michael addition and the hydrogenation steps in the large scale synthesis of polypropylenimine dendrimers have been improved: by adding ammonia during the hydrogenations the substrate concentrations can be increased 8 times, the catalyst concentration can be lowered 10 times and the average selectivity remains > 99.5% per conversion. The dimensions of the dendrimers have been studied with SANS and with molecular calculations.