Title: Effects of anatomical asymmetry in spatial priors on model-based segmentation of the brain MRI: A validation study
Authors: Srivastava, Siddharth ×
Maes, Frederik
Vandermeulen, Dirk
Van Paesschen, Wim
Dupont, Patrick
Suetens, Paul #
Issue Date: 2004
Publisher: Springer
Series Title: Lecture notes in computer science vol:3216 pages:327-334
Conference: 7th international conference on medical image computing and computer-assisted intervention - MICCAI 2004 location:Saint-Malo, France date:26-29 September 2004
Abstract: This paper examines the effect of bilateral anatomical asymmetry of spatial priors on the final tissue classification based on maximum-likelihood (ML) estimates of model parameters, in a model-based intensity driven brain tissue segmentation algorithm from (possibly multispectral) MR images. The asymmetry inherent in the spatial priors is enforced on the segmentation routine by laterally flipping the priors during the initialization stage. The influence of asymmetry on the final classification is examined by making the priors subject-specific using non-rigid warping, by reducing the strength of the prior information, and by a combination of both. Our results, both qualitative and quantitative, indicate that reducing the prior strength alone does not have arty significant impact on the segmentation performance, but when used in conjunction with the subject-specific priors, helps to remove the misclassifications due to the influence of the asymmetric priors.
Description: Srivastava S., Maes F., Vandermeulen D., Van Paesschen W., Dupont P., Suetens P., ''Effects of anatomical asymmetry in the spatial priors on model-based segmentation of the brain MRI : a validation study'', Lecture notes in computer science, vol. 3216, pp. 327-334, 2004 (Proceedings 7th international conference on medical image computing and computer-assisted intervention - MICCAI 2004, part I, September 26-29, 2004, Saint-Malo, France).
ISSN: 0302-9743
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Research Group Neurophysiology
ESAT - PSI, Processing Speech and Images
Research Group Experimental Neurology
Nuclear Medicine & Molecular Imaging
Laboratory for Cognitive Neurology
Laboratory for Epilepsy Research
× corresponding author
# (joint) last author

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