Author:

Keywords:

Science & Technology, Life Sciences & Biomedicine, Plant Sciences, ENDOPLASMIC-RETICULUM STRESS, TRANSCRIPTION FACTOR, NUCLEAR TRANSLOCATION, ENERGY SENSOR, SNRK1 KINASE, REDOX STATE, CELL-DEATH, ARABIDOPSIS, MITOCHONDRIAL, ACTIVATION, endoplasmic reticulum stress, ethylene, proteostasis, reactive oxygen species, sugars, unfolded protein response, Endoplasmic Reticulum Stress, Ethylenes, Reactive Oxygen Species, Sugars, Unfolded Protein Response, ABIOTIC STRESS, 0602 Ecology, 0607 Plant Biology, 0703 Crop and Pasture Production, Plant Biology & Botany, 3108 Plant biology

Abstract:

Upon stress, a trade-off between plant growth and defense responses defines the capacity for survival. Stress can result in accumulation of misfolded proteins in the endoplasmic reticulum (ER) and other organelles. To cope with these proteotoxic effects, plants rely on the unfolded protein response (UPR). The involvement of reactive oxygen species (ROS), ethylene (ETH), and sugars, as well as their crosstalk, in general stress responses is well established, yet their role in UPR deserves further scrutiny. Here, a synopsis of current evidence for ROS-ETH-sugar crosstalk in UPR is discussed. We propose that this triad acts as a major signaling hub at the crossroads of survival and death, integrating information from ER, chloroplasts, and mitochondria, thereby facilitating a coordinated stress response.