Author:

Keywords:

Science & Technology, Life Sciences & Biomedicine, Ecology, Evolutionary Biology, Environmental Sciences & Ecology, SACCHAROMYCES-SENSU-STRICTO, LAGER BREWING YEAST, NATURAL HYBRIDS, GENOME SEQUENCE, MOLECULAR CHARACTERIZATION, INDUSTRIAL APPLICATIONS, REPRODUCTIVE ISOLATION, RAPID IDENTIFICATION, CEREVISIAE, DOMESTICATION, Adaptation, Physiological, Beer, Hybridization, Genetic, Saccharomyces, Saccharomyces cerevisiae, STG/17/003#54272001, 12W3921N#55744514, 1S08821N#55263925, 1S80318N|1S80320N#54444808, 12W3918N#54511017, 3103 Ecology, 3104 Evolutionary biology, 4104 Environmental management

Abstract:

Hybridization between species often leads to non-viable or infertile offspring, yet examples of evolutionarily successful interspecific hybrids have been reported in all kingdoms of life. However, many questions on the ecological circumstances and evolutionary aftermath of interspecific hybridization remain unanswered. In this study, we sequenced and phenotyped a large set of interspecific yeast hybrids isolated from brewing environments to uncover the influence of interspecific hybridization in yeast adaptation and domestication. Our analyses demonstrate that several hybrids between Saccharomyces species originated and diversified in industrial environments by combining key traits of each parental species. Furthermore, posthybridization evolution within each hybrid lineage reflects subspecialization and adaptation to specific beer styles, a process that was accompanied by extensive chimerization between subgenomes. Our results reveal how interspecific hybridization provides an important evolutionary route that allows swift adaptation to novel environments.