Title: Peripheral ghrelin reduces food intake and respiratory quotient in chicken
Authors: Geelissen, SME ×
Swennen, Quirine
Van der Geyten, Serge
Kühn, Eduard
Kaiya, H
Kangawa, K
Decuypere, Eddy
Buyse, Johan
Darras, Veerle #
Issue Date: Feb-2006
Publisher: Elsevier science inc
Series Title: Domestic animal endocrinology vol:30 issue:2 pages:108-116
Abstract: Ghrelin injection, either centrally or peripherally strongly stimulates feeding in human and rodents. In contrast, centrally injected ghrelin inhibits food intake in neonatal chickens. No information is available about the mechanism and its relationship with energy homeostasis in chicken. Since ghrelin is predominantly produced in the stomach, we investigated the effect of peripherally injected ghrelin (1 nmol/100g body weight) on food intake and energy expenditure as measured in respiratory cells by indirect calorimetry for 24 h in one-week-old chickens. Plasma glucose, triglycerides, free fatty acids, total protein and T-3 were measured in a separate experiment until 60 min after injection. Food intake decreased until at least I h after intravenous ghrelin administration. The respiratory quotient (RQ) in ghrelin-injected chickens was reduced until 14h after administration whereas plasma glucose and triglycerides concentrations were not altered. Free fatty acids and total protein levels also remained unchanged. Ghrelin did not influence heat production and this was supported by the absence of changes in plasma T3 levels when compared to the control values.
ISSN: 0739-7240
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Division of Livestock-Nutrition-Quality (-)
Animal Physiology and Neurobiology Section - miscellaneous
× corresponding author
# (joint) last author

Files in This Item:
File Description Status SizeFormat
Geelissen et al_2006_Domestic Animal Endocrinology_vol30_p108-116.pdf Published 234KbAdobe PDFView/Open Request a copy

These files are only available to some KU Leuven Association staff members


All items in Lirias are protected by copyright, with all rights reserved.

© Web of science