Title: Myocardial beta-adrenergic receptor characteristics in T-3-induced ascites and in broiler lines differing in ascites susceptibility
Authors: Ladmakhi, MH ×
Buys, Nadine
Vanderpooten, Anita
Decuypere, Eddy #
Issue Date: Jun-1997
Publisher: Carfax publ co
Series Title: Avian pathology vol:26 issue:2 pages:293-303
Abstract: The present study was designed to investigate the myocardial beta-adrenergic receptor characteristics in T-3-induced ascites in two genetic lines of broilers, in order to look for possible involvement of myocardial beta-adrenergic receptors in the development of broiler ascites syndrome. Myocardial membrane fractions were prepared from 6 and 8 week old chickens fed a 1.5 parts/10(6) T-3 supplemented diet from day 1 in order to increase ascites incidence. Also, a similar assay was performed on myocardial cells of ascites sensitive and ascites resistant chickens at 5 weeks of age. The binding capacity and binding affinity of the myocardial beta-adrenergic receptor of the two genetic lines of birds did not differ significantly, but the tendency of beta-adrenergic receptor binding capacity and affinity constants in ascites-sensitive birds was slightly higher compared to ascites-resistant birds. In commercial broilers, although dietary T-3 significantly increased ascites mortality and the RV/TV ratio compared to control, it did not affect significantly beta-adrenergic receptor characteristics.
ISSN: 0307-9457
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Division of Gene Technology (-)
Division of Livestock-Nutrition-Quality (-)
× corresponding author
# (joint) last author

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