Title: Influence of feeding pattern on thyroid hormones in long-term food-restricted rats
Authors: Cokelaere, Marnix ×
Decuypere, Eddy
Flo, Gerda
Darras, Veerle
Kühn, Eduard #
Issue Date: Jul-1996
Publisher: Georg thieme verlag
Series Title: Hormone and metabolic research vol:28 issue:7 pages:315-318
Abstract: The effect of a long-term 50% food restriction on plasma thyroid hormone levels was studied in adult male rats, which received their reduced daily amount of food either as one meal or 5 different meals. Compared to controls, a long-term food restriction reduced total 24 h-mean plasma T4, T3 and TSH concentrations. The total T4 level was more reduced in rats fed their reduced ration in one meal than in rats given food in several meals. This resulted in a higher T3/T4 ratio in the former group of rats than in the other groups (free access to food; food in several meals). In the control group and in the food-restricted group receiving their food in one meal, significant diurnal variations in total T4, T3 and TSH levels were seen. The T3 rhythm was abolished in food-restricted rats receiving their food spread over several meals, but T4 and TSH rhythms were not. We conclude that total peripheral thyroid hormone levels in food-restricted rats are influenced, not only by the amount of food but also by the feeding pattern.
ISSN: 0018-5043
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Faculty of Medicine, Campus Kulak Kortrijk
Division of Livestock-Nutrition-Quality (-)
Interdisciplinary Research Facility Life Sciences, Campus Kulak Kortrijk
Animal Physiology and Neurobiology Section - miscellaneous
× corresponding author
# (joint) last author

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