Title: Growth and carcass composition in broiler-type chickens following passive immunization of insulin-like growth factor-2 (IGF-2) between 2 and 4 weeks of age
Authors: Spencer, GSG ×
Decuypere, Eddy
Buyse, Johan
Lamosova, D
Hodgkinson, SC
Bass, JJ
Zeman, M #
Issue Date: Mar-1997
Publisher: Pergamon-elsevier science ltd
Series Title: Comparative biochemistry and physiology c-pharmacology toxicology & endocrinology vol:116 issue:3 pages:239-243
Abstract: Ten broiler-type chickens at 2 weeks of age were injected daily with 0.5 mi of normal sheep serum while 10 others were similarly injected with 0.5 mi of a sheep anti-IGF-2 serum. Immunization with anti-IGF-2 serum had no significant effect upon body weight gain, on carcass composition, on appetite or food conversion. Liver weight was significantly increased (P < 0.05) in the anti-IGF-2 birds, but there was-no effect on the weight of any other organ measured. The proportion of breast muscle in the carcass of anti-IGF-2 treated birds was significantly lower (P < 0.01) than in the controls and they also had 27% less abdominal fat. In acute studies, anti-IGF-2 administration caused an elevation in plasma GH, but in the longer term neither plasma GH nor plasma T-3 concentrations were significantly affected by immunization against IGF-2. These results suggest that circulating IGF-2 is not a major regulator of overall somatic growth in chickens, but may have an effect on muscle and fat deposition. (C) 1997 Elsevier Science Inc.
ISSN: 0742-8413
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Division of Livestock-Nutrition-Quality (-)
× corresponding author
# (joint) last author

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