Title: Haplotype sharing refines the location of an imprinted quantitative trait locus with major effect on muscle mass to a 250-kb chromosome segment containing the porcine IGF2 gene
Authors: Nezer, C ×
Collette, C
Moreau, L
Brouwers, B
Kim, JJ
Giuffra, E
Buys, Nadine
Andersson, L
Georges, M #
Issue Date: Sep-2003
Publisher: Genetics Society of America
Series Title: Genetics vol:165 issue:1 pages:277-285
Abstract: We herein describe the fine mapping of an imprinted QTL with major effect on muscle mass that was previously assigned to distal SSC2p in the pig. The proposed approach exploits linkage disequilibrium in combination with QTL genotyping by marker-assisted segregation analysis. By identifying a haplotype shared by all "Q" chromosomes, we map the QTL to an similar to250-kb chromosome segment containing INS and IGF2 as the only known paternally expressed genes. This considerably reinforces the candidacy of these genes, justifying their detailed analysis.
ISSN: 0016-6731
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Division of Gene Technology (-)
× corresponding author
# (joint) last author

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