Title: Partial food restriction increases hepatic inner ring deiodinating activity in the chicken and the rat
Authors: Darras, Veerle ×
Cokelaere, Marnix
Dewil, Erna
Arnouts, S
Decuypere, Eddy
Kühn, Eduard #
Issue Date: Dec-1995
Publisher: Academic press inc jnl-comp subscriptions
Series Title: General and Comparative Endocrinology vol:100 issue:3 pages:334-338
Abstract: The effects of a long term partial food restriction were studied in chickens and rats. In chickens the treatment resulted in increased plasma T-4 levels while T-4 levels in rats remained unchanged. Plasma T-3 decreased in both species. In vitro hepatic outer ring deiodinating type I (ORD-I) activity was not influenced by the food restriction, suggesting that the amount of ORD-I enzyme present in the liver remained unchanged. In vitro hepatic inner ring deiodinating type III activity, on the contrary, was greatly increased in both species. This increase may contribute to the decreased circulating T-3 levels by increasing the degradation of T-3 and diverting the deiodination of T-4 to rT(3) instead of to T-3. (C) 1995 Academic Press, Inc.
ISSN: 0016-6480
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Animal Research Center
Division of Livestock-Nutrition-Quality (-)
Interdisciplinary Research Facility Life Sciences, Campus Kulak Kortrijk
Animal Physiology and Neurobiology Section - miscellaneous
× corresponding author
# (joint) last author

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