Title: Mass spectrometric analysis of the perisympathetic organs in locusts: identification of novel periviscerokinins
Authors: Clynen, Elke
Huybrechts, Jurgen
De Loof, Arnold
Schoofs, Liliane # ×
Issue Date: Jan-2003
Publisher: Academic Press
Series Title: Biochemical and Biophysical Research Communications vol:300 issue:2 pages:422-428
Abstract: A mass spectrometric analysis carried out to determine the peptidome of the abdominal perisympathetic organs in the locust species Locusta migratoria and Schistocerca gregaria yielded a number of predominant ion peaks, among which are Lom-PVK (AAGLFQFPRVamide) and Scg-MT-2 (TSSLFPHPRLamide). In addition. three novel peptides were identified: Lom-PVK-2 (identical in Schistocerca): GLLAFPRVamide, Lom-PVK-3: DGGEPAAPLWFGPRVamide, and Scg-PVK-3: DGAETPGAAA SLWFGPRVamide. An extensive mass spectrometric study of the central nervous system showed that the periviscerokinins (-PRVamides) and Scg-MT-2 (-FXXPRLamide) are restricted to the abdominal ganglia and their perisyrnpathetic organs, while the pyrokinins (-FXPRLamides) are present only in the brain-retrocerebral complex. Sequence comparison with the Drosophila genes supports a conserved gene structure whereby a capabilith-like gene encodes the periviscerokinins that are expressed in the abdominal ganglia and stored in the perisympathetic organs, while a hugin-like gene encodes the pyrokinins that are expressed in the head ganglia and stored in the retrocerebral complex. (C) 2002 Elsevier Science (USA). All rights reserved.
ISSN: 0006-291X
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Animal Physiology and Neurobiology Section - miscellaneous
Department of Biology - miscellaneous
× corresponding author
# (joint) last author

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