Title: "Insects do not have sex hormones": A myth?
Authors: De Loof, Arnold ×
Huybrechts, Roger #
Issue Date: Sep-1998
Publisher: Academic press inc
Series Title: General and Comparative Endocrinology vol:111 issue:3 pages:245-260
Abstract: Mammals have two genes (SRY and DMT1) for testis formation-androgenesis, an anti-testis gene, DAX1, an anti-Mullerian duct hormone, and steroid sex hormones. Drosophila uses the sex-lethal, transformer and doublesex genes for sexual differentation and is supposed to lack sex hormones. However, the statement that insects do not have sex hormones loses much of its credibility if one considers (1) the classical endocrinological work on sexual differentiation in the firefly Lampyris and in the hevea tussock moth Orgyia; (2) the recent identification of an androgenic hormone and its role in sex determination in the isopod Armadillidium; (3) the similarity between steroidogenic factor 1 (SF-1) of mammals and fushi tarazu factor 1 (FTZ-F1) of Drosophila; and (4) the steroidogenic effect of gonadotropins secreted by the brain of female locusts and mosquitoes and of male gypsy moth. In our model, based on data from the literature, ecdysone, when present in high concentrations, might function as an androgenic sex steroid. It is also the precursor of 20-OH-ecdysone, which is the moulting hormone of insects, and in vitellogenic females of many species, the counterpart of estrogens as well. Other gender-specific hormones are likely to exist in the brain-gonad axis. (C) 1998 Academic Press.
ISSN: 0016-6480
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Animal Physiology and Neurobiology Section - miscellaneous
Department of Biology - miscellaneous
× corresponding author
# (joint) last author

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