Title: Metabolism of injected [3H]ecdysone in male Sarcophaga bullata (Diptera)
Authors: Briers, T ×
De Clerck, D
Vanbeek, E
De Loof, Arnold #
Issue Date: Nov-1983
Publisher: Academic press inc jnl-comp subscriptions
Series Title: General and Comparative Endocrinology vol:52 issue:3 pages:379-387
Abstract: Within 30 min after injection, [3H]ecdysone was rapidly partially metabolized to ecdysterone and other ecdysteroids. After 8 hr most (99%) of the tritiated material had disappeared from the hemolymph. In testes, the predominant ecdysteroid appeared to be ecdysterone but no accumulation occurred. Comparison of the dynamics of the ecdysone metabolism in abdomens and head-thorax sections showed that in the head-thorax ecdysterone was the major component, whereas in abdomens the major metabolites were highly polar products (HPP). However, the total amount of label was nearly the same in both parts. Two groups of HPP have been isolated from the abdomen fractions without testes: HPP B and HPP C. Only HPP B could be hydrolyzed by enzymes and seemed at least to contain glucuronides, beta-glucosides, and sulfate conjugates. After 4 hr most of the tritiated ecdysteroids were found in the fecal material. No male-specific metabolites have been discovered.
ISSN: 0016-6480
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Department of Biology - miscellaneous
× corresponding author
# (joint) last author

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