Title: Pax-6 in development and evolution
Authors: Callaerts, Patrick ×
Halder, Georg
Gehring, WJ #
Issue Date: 1997
Publisher: Annual reviews inc
Series Title: Annual review of neuroscience vol:20 pages:483-532
Abstract: Pax-6 is a member of the Par gene class and encodes a protein containing a paired domain and a homeodomain. The molecular characterization of Pax-6 genes from species of different animal phyla and the analysis of Pax-6 function in the developing eyes and central nervous system of vertebrates, Drosophila melanogaster, and Caenorhabditis elegans suggest that Pax-6 homologues share conserved functions. In this review, we present recent data on the structural and functional characterization of Pax-6 homologues from species of different animal phyla. We discuss the implications of these findings for our understanding of the development and evolution of eyes and nervous systems.
ISSN: 0147-006X
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Associated Laboratories - miscellaneous (-)
Department of Human Genetics - miscellaneous
× corresponding author
# (joint) last author

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