Title: Lectin-binding sites during drosophila embryogenesis
Authors: Callaerts, Patrick ×
Vulsteke, Veerle
Peumans, Willy
De Loof, Arnold #
Issue Date: Mar-1995
Publisher: Springer verlag
Series Title: Rouxs archives of developmental biology vol:204 issue:4 pages:229-243
Abstract: The spectrum of lectin binding sites as it emerges during embryonic development of Drosophila was analysed by means of fluorescein-labelled lectins. As development and morphogenesis proceed, the reaction pattern becomes more and more complex. Mannose/glucose-, mannose-, N-acetylglucosamine- and poly-N-acetylglucosamine-specific lectins bind ubiquitously. Nuclear envelopes only have binding sites for wheat germ agglutinin. N-acetylgalactosamine-binding lectins are specific for ectodermal derivatives. Gal beta 1-3-N-acetylgalactosamine-binding lectins are highly selective markers for neural structures, haemocytes and Garland cells. It is also shown that Drosophila laminin is differentially glycosylated. The possible implications of differential and germ layer-specific glycosylation are discussed.
ISSN: 0930-035X
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Associated Laboratories - miscellaneous (-)
Division of Crop Biotechnics
Department of Biology - miscellaneous
Molecular Genetics Section (-)
Department of Human Genetics - miscellaneous
× corresponding author
# (joint) last author

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