Title: cDNA cloning and transcript distribution of two different neuroparsin precursors in the desert locust, Schistocerca gregaria
Authors: Janssen, Tom ×
Claeys, Ilse
Simonet, Gert
De Loof, Arnold
Girardie, J
Vanden Broeck, Jozef #
Issue Date: Apr-2001
Publisher: Blackwell science ltd
Series Title: Insect molecular biology vol:10 issue:2 pages:183-189
Abstract: Neuroparsins were originally identified in locust corpus cardiacum extracts as folliculostatic or 'antigonadotropic' neuropeptides. This paper presents the cloning of two different neuroparsin precursor cDNAs from the brain of the desert locust, Schistocera gregaria, The first transcript encodes the precursor (Scg-NPP1) of S, gregeria neuroparsin A and B, whereas the second codes for a novel neuroparsin-related peptide precursor (Scg-NPP2), Both precursors display significant sequence similarities with each other and with the Locusts migratoria neuroparsin (Lom-NPP) and Aedes aegypti ovary ecdysteroidogenic hormone (Aea-OEH1) precursors. Northern blot analysis revealed that these neuroparsin transcripts are present in larval and adult locust brains. Interestingly, the Scg-NPP2 mRNA content proved to be strongly regulated during the reproductive cycle in bath adult males and females.
ISSN: 0962-1075
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Animal Physiology and Neurobiology Section - miscellaneous
Department of Biology - miscellaneous
× corresponding author
# (joint) last author

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