Title: Effect of route and frequency of administration of apomorphine on growth hormone release in African catfish (Clarias gariepinus)
Authors: Lescroart, Olivier ×
Roelants, Ivo
Cauwenberghs, Nancy
De Schrijver, Remi
Kuhn, ER
Ollevier, Frans #
Issue Date: Apr-1997
Publisher: Pergamon-elsevier science ltd
Series Title: Life Sciences vol:60 issue:20 pages:1771-1779
Abstract: Apomorphine is known to stimulate growth hormone release in African catfish following an intraperitoneal (IF) injection. In the present study the effect of apomorphine (5 or 20 mg/kg body weight) on plasma GH levels was evaluated after gastro-intestinal or parenteral delivery. Apomorphine increased the plasma GH concentration regardless of the route of administration, indicating that apomorphine can be absorbed from the intestinal tract. The effect of repeated administration of apomorphine differed clearly between the tested doses. Although a single IP injection with 20 mg apomorphine/kg body weight resulted in a clear increase in plasma GH levels, a second injection given 12 hours later was ineffective. In contrast the last of 4 consecutive injections with 5 mg apomorphine/kg body weight given at intervals of 12 hours stimulated the plasma GH levels in a similar way to a single IP injection with the same dose.
ISSN: 0024-3205
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Faculty of Science, Campus Kulak Kortrijk
Division of Livestock-Nutrition-Quality (-)
Ecology, Evolution and Biodiversity Conservation Section
× corresponding author
# (joint) last author

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