Biochemical and Biophysical Research Communications vol:241 issue:2 pages:530-534
From an acid methanolic extract of about 7000 brains of the desert locust (Schistocerca gregaria) two novel neuropeptides, schistomyotropin-1 (Scg-MT-1) and schistomyotropin-2! (Scg-MT-2), were isolated and identified. Their primary structures are GAAPAAQFSPRLamide (Scg-MT-1) and TSSLFPHPRLamide (Scg-MT-2). Scg-MT-1 belongs to the locustamyotropin family characterized by its FXPRLamide C-terminus. Scg-MT-2 has a similar carboxyl end with the F-residue one position further away hom the C-terminus. This may account for its being 10 times less active then Scg-MT-1 in stimulating cockroach hindgut motility. (C) 1997 Academic Press.