Title: 20-hydroxyecdysone and juvenile hormone regulate the laminarin-induced nodulation reaction in larvae of the flesh fly, Neobellieria bullata
Authors: Franssens, Vanessa ×
Smagghe, Guy
Simonet, Gert
Claeys, Ilse
Breugelmans, Bert
De Loof, Arnold
Vanden Broeck, Jozef #
Issue Date: 2006
Publisher: Elsevier
Series Title: Developmental and Comparative Immunology vol:30 issue:9 pages:735-740
Abstract: Nodulation, which is considered the predominant defense reaction to infection in insects, is a complex process influenced by various endogenous factors. However, the precise mechanisms underlying nodulation remain largely unknown. In the present study, we examined the influence of the insect hormones 20-hydroxyecdysone (20E) and juvenile hormone (JH) on the laminarin-induced nodulation reaction in larvae of the flesh fly Neobellieria bullata. Treating third-instar larvae of N. bullata with 20E prior to laminarin injection enhanced the nodulation response in a dose-dependent manner. The ecdysone agonists RH2485, RH5849 and RH0345 similarly enhanced the nodulation reaction, although they were less active than 20E. In contrast to ecdysone stimulation, supplying larvae with JH or the juvenile hormone analogs (JHA), fenoxycarb and pyriproxyfen, significantly impaired their ability to form nodules in response to laminarin. These findings demonstrate for the first time that 20E and JH play an important regulatory role in the nodulation process. (c) 2005 Elsevier Ltd. All rights reserved.
ISSN: 0145-305X
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Animal Physiology and Neurobiology Section - miscellaneous
Department of Biology - miscellaneous
Molecular Physiology of Plants and Micro-organisms Section - miscellaneous
× corresponding author
# (joint) last author

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