Title: Pax6 in the sepiolid squid Euprymna scolopes: evidence for a role in eye, sensory organ and brain development
Authors: Hartmann, B ×
Lee, PN
Kang, YY
Tomarev, S
de Couet, HG
Callaerts, Patrick #
Issue Date: Feb-2003
Publisher: Elsevier science bv
Series Title: Mechanisms of development vol:120 issue:2 pages:177-183
Abstract: The cloning of a Pax6 orthologue from the sepiolid squid Euprymna scolopes and its developmental expression pattern are described. The data are consistent with the presence of a single gene encoding a protein with highly conserved DNA-binding paired and homeodomains. A detailed expression analysis by in situ hybridization and immunodetection revealed Pax6 mRNA and protein with predominantly nuclear localization in the developing eye, olfactory organ, brain lobes (optic lobe, olfactory lobe, peduncle lobe, superior frontal lobe and dorsal basal lobe), arms and mantle, suggestive of a role in eye, brain, and sensory organ development. (C) 2002 Elsevier Science Ireland Ltd. All rights reserved.
ISSN: 0925-4773
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Associated Laboratories - miscellaneous (-)
Department of Human Genetics - miscellaneous
× corresponding author
# (joint) last author

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