Title: Identification of tryptophan and beta-carboline as paralysins in larvae of the yellow mealworm, Tenebrio molitor
Authors: Kotanen, S
Huybrechts, Jurgen
Cerstiaens, Anja
Zoltan, K
Daloze, D
Baggerman, Geert
Forgo, P
De Loof, Arnold
Schoofs, Liliane # ×
Issue Date: Oct-2003
Publisher: Academic Press
Series Title: Biochemical and Biophysical Research Communications vol:310 issue:1 pages:64-71
Abstract: Acidic methanolic, whole body extracts of larval Tenebrio molitor (Insecta, Coleoptera) and other juvenile insects are highly toxic to adults of the same species and other species: injection causes instant paralysis to death. Referring to their dramatic effect in mature insects, the responsible compounds have been designated as "paralysins." Two paralysins have already been identified in the flesh fly, Neobellieria bullata, i.e., beta-alanine-tyrosine (BAY) and 3-hydroxykynurenine (3HK). We report here the isolation, from larval T molitor, of two additional paralysins, respectively, the essential amino acid, tryptophan (Trp), and the saturated beta-carboline, 1,2,3,4,-tetrahydro-beta-carboline-3-carboxylic acid (THCA). (C) 2003 Elsevier Inc. All rights reserved.
ISSN: 0006-291X
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Animal Physiology and Neurobiology Section - miscellaneous
Department of Biology - miscellaneous
Microbial and Molecular Systems - miscellaneous
× corresponding author
# (joint) last author

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