Title: pH 48 h after onset of extracorporeal membrane oxygenation is an independent predictor of survival in patients with respiratory failure
Authors: Rega, Filip ×
Evrard, Veerle
Bollen, Hilde
Peeters, Geert
Vercaemst, Leen
Meuris, Bart
Herijgers, Paul
Sergeant, Paul
Hermans, Greet
Vlasselaers, Dirk
Meyns, Bart #
Issue Date: 22-May-2007
Publisher: Blackwell Science
Series Title: Artificial Organs vol:31 issue:5 pages:384-9
Abstract: Extracorporeal membrane oxygenation (ECMO) is a life-saving procedure in patients with severe respiratory failure, unresponsive to conventional therapy. We reviewed our series of 70 ECMO runs (April 1997 to December 2005) in patients with respiratory distress, refractory to standard ventilation. Survival at 90 days was 42.7%. Besides age, we found no statistical significant difference in patient demographics or preoperative patient data between survivors and nonsurvivors. Univariate analyses indicated that pH values at 24 and 48 h after onset of ECMO were significantly higher in survivors. In multivariate analysis, age and pH at 48 h remained independent predictors of survival. ECMO in respiratory failure saves lives. No other demographic or preoperative, patient-related parameter than age was identified as predictor of survival. Although there was no difference in pH at onset of ECMO, blood gas analysis at 48 h revealed pH as an independent predictor of survival.
ISSN: 0160-564X
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Experimental Cardiac Surgery
Clinical Cardiac Surgery
Laboratory for Clinical Infectious and Inflammatory Disorders
Laboratory of Intensive Care Medicine
× corresponding author
# (joint) last author

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