Author:

Keywords:

NMR, instrumentation, miniaturization, table-top NMR, portable MRI, microfluidics, magnetic resonance engineering, Science & Technology, Physical Sciences, Chemistry, Multidisciplinary, Chemistry, SINGLE-SIDED NMR, LIQUID-STATE NMR, TO-NOISE RATIO, HYPERPOLARIZED HE-3, HIGH-RESOLUTION, PARA-HYDROGEN, SPIN NOISE, SIGNAL, SPECTROSCOPY, SAMPLES, 03 Chemical Sciences, General Chemistry, 34 Chemical sciences

Abstract:

Sixty six years after its discovery, magnetic resonance deserves the qualification of a mature technique. This paper presents the state of the art of the instrumentation in NMR and MRI. Superconducting magnets are at the heart of the NMR instruments and their performances towards high magnetic fields target high resolution and high precision applications. On the other hand, miniature systems could answer to questions that are not currently answered like the analysis outside the laboratory and in the field, chemical analysis on microfluidic chips, or systems for dedicated organ imaging. Here are presented the use of permanent magnets and specialized detectors as novel paths towards miniaturization, signal enhancement methods by hyperpolarization in order to show their potential towards coupled applications offering high sensitivity information, and finally, innovative applications that could have interest in cancer biomedicine.