Title: Alterations of mitochondrial DNA in CEM cells selected for resistance toward ddC toxicity
Authors: Bjerke, M ×
Franco, M
Johansson, M
Balzarini, Jan
Karlsson, A #
Issue Date: 4-Oct-2006
Publisher: Marcel Dekker
Series Title: Nucleosides, Nucleotides & Nucleic Acids vol:25 issue:9-11 pages:987-90
Conference: 10th European/12th International Meeting on Purines and Pyrimidines location:Prague, Czech Republic date:9-12 June 2005
Abstract: 2 ',3 '-dideoxycytidine (ddC) is a nucleoside analog that has been shown to produce a delayed toxicity which may be due to the depletion of mitochondrial DNA (mtDNA). In order to gain further understanding of the events involved in mitochondrial toxicity, two different CEM cell lines were selected for resistance to the delayed ddC toxicity.
ISSN: 1525-7770
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Laboratory of Virology and Chemotherapy (Rega Institute)
× corresponding author
# (joint) last author

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