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Title: d4TMP delivery from 7-substituted cycloSal-d4TMPs
Authors: Meier, C ×
Renze, J T
Balzarini, Jan
De Clercq, Erik #
Issue Date: 28-Oct-2003
Series Title: Nucleosides, nucleotides & nucleic acids vol:22 issue:5-8 pages:825-7
Conference: XV International Round Table on "Nucleosides, Nucleotides and Their Biological Applications" location:Leuven, Belgium date:10-14 September 2002
Abstract: Benzyl-substituted cycloSal-d4T monophosphates were prepared and evaluated for their ability to release d4TMP selectively. In contrast to previously reported derivatives, two of the new compounds release d4TMP as the sole product while two others gave the expected benzyl phosphate diesters. However, these diesters were surprisingly stable against degradation to release d4TMP.
ISSN: 1525-7770
Publication status: published
KU Leuven publication type: IC
Appears in Collections:Laboratory of Virology and Chemotherapy (Rega Institute)
× corresponding author
# (joint) last author

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