Title: Synthesis and biological evaluation of pyridin-2-one nucleosides
Authors: Huntley, C M ×
Cotterill, A S
Maillard, J Y
Balzarini, Jan
Simons, C #
Issue Date: 27-Sep-2001
Host Document: Nucleosides, nucleotides & nucleic acids vol:20 issue:4-7 pages:731-3
Conference: XIV International Round Table on "Nucleosides, Nucleotides and Their Biological Applications" location:San Francisco, CA, USA date:10-14 September 2000
Abstract: The synthesis of 1-(beta-D-ribofuranosyl)pyridin-2-one-3-carboxylic acid and the 3-carboxamide as well as a short series of 3N-carboxamides, prepared by TPTU/HOBt coupling of primary amines with 1-(beta-D-ribofuranosyl)pyridin-2-one-3-carboxylic acid, and their evaluation as anti-infective agents is described.
ISSN: 1525-7770
Publication status: published
KU Leuven publication type: IC
Appears in Collections:Laboratory of Virology and Chemotherapy (Rega Institute)
× corresponding author
# (joint) last author

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