Title: 4"-H-TSAO-T, a novel prototype in the HIV-1 specific TSAO family
Authors: Lobatón, E ×
Velázquez, S
San-Félix, A
De Clercq, Erik
Balzarini, Jan
Camarasa, M J #
Issue Date: 27-Sep-2001
Publisher: Marcel Dekker
Series Title: Nucleosides, Nucleotides & Nucleic Acids vol:20 issue:4-7 pages:711-714
Conference: XIV International Round Table on "Nucleosides, Nucleotides and Their Biological Applications" location:San Francisco, CA, USA date:10-14 September 2000
Abstract: The first TSAO derivative that lacks the amino group at the 3'-spiro moiety has been prepared. This molecule retained its HIV-1 specificity (NNRTI characteristic) but did not select for any of the classical NNRTI-specific mutations in the NNRTI binding pocket, including 138-Lys (TSAO resistant strain).
ISSN: 1525-7770
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Laboratory of Virology and Chemotherapy (Rega Institute)
× corresponding author
# (joint) last author

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