ITEM METADATA RECORD
Title: CycloSal-2'-ara(ribo)-fluoro-2',3'-dideoxyadenosine monophosphates--an effort to solve the structure-activity relationship of 2'-fluoro-ddA
Authors: Meier, C ×
Knispel, T
Marquez, V E
De Clercq, Erik
Balzarini, Jan #
Issue Date: 26-Aug-1999
Host Document: Nucleosides & nucleotides vol:18 issue:4-5 pages:907-12
Conference: XIIIth International Round Table of Nucleosides, Nucleotides, and their Biological Applications location:Montpellier, France date:6-10 September 1998
Abstract: Novel lipophilic cycloSal-triesters 3 and 4 from the ara- and ribo-configurated 2'-fluorinated ddAs 1 and 2, respectively, were prepared. The title compounds 3 and 4 delivered the corresponding monophosphates and thus, increasing the bioactivity or convert a formerly inactive compound into a RT inhibitor.
ISSN: 0732-8311
Publication status: published
KU Leuven publication type: IC
Appears in Collections:Laboratory of Virology and Chemotherapy (Rega Institute)
× corresponding author
# (joint) last author

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