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Catheterization and Cardiovascular Interventions

Publication date: 2016-11-01
Volume: 88 Pages: 843 - 853
Publisher: Wiley-Liss

Author:

Bennett, Johannes
Adriaenssens, Tom ; Desmet, W ; Dubois, C

Keywords:

Science & Technology, Life Sciences & Biomedicine, Cardiac & Cardiovascular Systems, Cardiovascular System & Cardiology, coronary bifurcation, dedicated devices, bioresorbable scaffolds, optical coherence tomography, OPTICAL COHERENCE TOMOGRAPHY, PERCUTANEOUS CORONARY INTERVENTION, VASCULAR SCAFFOLD, ELUTING STENT, MYOCARDIAL-INFARCTION, SYSTEM, OUTCOMES, CONSENSUS, IMPLANTATION, NARROWINGS, Absorbable Implants, Coronary Angiography, Coronary Artery Disease, Coronary Vessels, Drug-Eluting Stents, Female, Humans, Middle Aged, Prosthesis Design, Sirolimus, Tissue Scaffolds, Tomography, Optical Coherence, Treatment Outcome, 1102 Cardiorespiratory Medicine and Haematology, Cardiovascular System & Hematology, 3201 Cardiovascular medicine and haematology

Abstract:

There is an ongoing controversy regarding the efficacy and safety of different percutaneous stenting techniques for coronary bifurcation lesions needing >1 stent. The promise of safe vessel restoration with bioresorbable scaffolds (BRS) may not be transferable to complex double BRS bifurcation techniques, and permanent metallic scaffolding of the bifurcation core may be needed. We identified modified-T stenting as the most promising fully bioresorbable 2-stent strategy in a preclinical setting. The objective of this study is to assess acute performance and compare long-term vessel healing with this strategy, versus an approach combining BRS with a dedicated metallic drug-eluting bifurcation stent.