Title: Novel approaches for preventing acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation
Authors: Servais, Sophie ×
Beguin, Yves
Delens, Loic
Ehx, Grégory
Fransolet, Gilles
Hannon, Muriel
Willems, Evelyne
Humblet-Baron, Stephanie
Belle, Ludovic
Baron, Frédéric # ×
Issue Date: Aug-2016
Series Title: Expert Opinion on Investigational Drugs vol:25 issue:8 pages:957-972
Abstract: Allogeneic hematopoietic stem cell transplantation (alloHSCT) offers potential curative treatment for a wide range of malignant and nonmalignant hematological disorders. However, its success may be limited by post-transplant acute graft-versus-host disease (aGVHD), a systemic syndrome in which donor's immune cells attack healthy tissues in the immunocompromised host. aGVHD is one of the main causes of morbidity and mortality after alloHSCT. Despite standard GVHD prophylaxis regimens, aGVHD still develops in approximately 40-60% of alloHSCT recipients.
ISSN: 1354-3784
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Laboratory of Genetics of Autoimmunity (VIB-KU Leuven Center for Brain & Disease Research)
× corresponding author
# (joint) last author

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