Title: Tacrolimus-related polyneuropathy: case report and review of the literature
Authors: De Weerdt, Annick ×
Claeys, Kristl
De Jonghe, Peter
Ysebaert, Dirk
Chapelle, Thiery
Roeyen, Geert
Jorens, Philippe G #
Issue Date: Mar-2008
Publisher: Van Gorcum
Series Title: Clinical Neurology and Neurosurgery vol:110 issue:3 pages:291-294
Abstract: Patients, in particular recipients of orthotopic liver transplants, receiving the immunosuppressant tacrolimus (FK-506), are at risk for developing central neurotoxic adverse events. We report the occurrence of a tacrolimus-induced peripheral neurotoxic event, i.e. pure motor axonal polyneuropathy of the lower limbs in a 44-year-old woman, 9 days after combined orthotopic liver and pancreas transplantation. She was treated for 5 days with intravenous immunoglobulins. Partial recovery followed over months to years. An overview of all 11 reported FK506-associated polyneuropathies is given.
ISSN: 0303-8467
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Laboratory for Muscle Diseases and Neuropathies
× corresponding author
# (joint) last author

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