Heritable components of the human fecal microbiome are associated with visceral fat
Beaumont, Michelle Goodrich, Julia K Jackson, Matthew A Yet, Idil Davenport, Emily R Vieira-Silva, Sara Manuel Debelius, Justine Pallister, Tess Mangino, Massimo Raes, Jeroen Knight, Rob Clark, Andrew G Ley, Ruth E Spector, Tim D Bell, Jordana T # ×
BioMed Central Ltd.
Genome Biology vol:17 issue:1 pages:189
Variation in the human fecal microbiota has previously been associated with body mass index (BMI). Although obesity is a global health burden, the accumulation of abdominal visceral fat is the specific cardio-metabolic disease risk factor. Here, we explore links between the fecal microbiota and abdominal adiposity using body composition as measured by dual-energy X-ray absorptiometry in a large sample of twins from the TwinsUK cohort, comparing fecal 16S rRNA diversity profiles with six adiposity measures.