Title: Cortical neurogenesis from pluripotent stem cells: complexity emerging from simplicity
Authors: Anderson, Stewart
Vanderhaeghen, Pierre # ×
Issue Date: Aug-2014
Publisher: Elsevier Science Ltd.
Series Title: Current Opinion in Neurobiology vol:27
Article number: 10.1016/j.conb.2014.03.012
Abstract: The cerebral cortex contains dozens of neuronal subtypes grouped in specific layers and areas. Recent studies have revealed how embryonic and induced pluripotent stem cells (PSC) can differentiate into a wide diversity of cortical neurons in vitro, while recapitulating many of the temporal and spatial features that characterize corticogenesis. PSC-derived neurons can integrate into the brain following in vivo transplantation and display patterns of morphology and connectivity specific of cortical neurons. PSC-corticogenesis thus emerges as a robust model that provides new ways to link cortical development, evolution, and disease.
ISSN: 0959-4388
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Non-KU Leuven Association publications
× corresponding author
# (joint) last author

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