ITEM METADATA RECORD
Title: Design and synthesis of bio-isosteres of thymidine triphosphate
Authors: Goldring, A O ×
Balzarini, Jan
Gilbert, I H #
Issue Date: May-1998
Series Title: Bioorganic & medicinal chemistry letters vol:8 issue:10 pages:1211-4
Abstract: This paper describes the design and synthesis of potential isosteres of triphosphates which should show enhanced metabolic stability and lipophilicity compared to triphosphates. The triphosphate isosteres were then linked to nucleosides and evaluated for their inhibitory activity against HIV infection.
URI: 
ISSN: 0960-894X
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Laboratory of Virology and Chemotherapy (Rega Institute)
× corresponding author
# (joint) last author

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