European Journal of Gastroenterology & Hepatology
Author:
Keywords:
Science & Technology, Life Sciences & Biomedicine, Gastroenterology & Hepatology, IMMUNE-MEDIATED DISEASES, VARICELLA-ZOSTER-VIRUS, RHEUMATOID-ARTHRITIS, PARKINSONS-DISEASE, ESOPHAGEAL ACHALASIA, AUTOIMMUNE-DISEASES, LEWY BODIES, MYENTERIC PLEXUS, MEASLES-VIRUS, ASSOCIATION, Adult, Alleles, Autoimmune Diseases, Case-Control Studies, Chickenpox, Comorbidity, Esophageal Achalasia, Europe, Family, Female, Genotype, HLA-DQ beta-Chains, Herpes Zoster, Herpesvirus 3, Human, Heterozygote, Humans, Hypersensitivity, Male, Middle Aged, Phenotype, Pregnancy, Pregnancy Complications, Psoriasis, Sjogren's Syndrome, Virus Diseases, White People, 1103 Clinical Sciences, 3202 Clinical sciences
Abstract:
Although an eight-residue insertion in HLA-DQβ1 has been recently identified as a genetic risk factor for idiopathic achalasia, other risk factors are still unknown. In the present study, we carried out an epidemiological survey and a genotype-phenotype (G×P) analysis to gain further insights into the etiology of achalasia.