Title: The importance of importance
Authors: Gleiss, Andreas ×
Zeillinger, Robert
Braicu, Elena I
Trillsch, Fabian
Vergote, Ignace
Schemper, Michael #
Issue Date: Jul-2016
Publisher: Kluwer Academic Publishers
Series Title: Annals of Oncology vol:27 issue:7 pages:1185-1189
Article number: mdw159
Abstract: We define the notion ofimportanceof prognostic factors in studies of survival, and suggest quantifying it by the Schemper-Henderson measure of explained variation. Conceptual differences to the standard approach for the statistical analysis of oncologic studies of survival are discussed and exemplified by means of a study of ovarian cancer. Explained variation permits to establish a ranking of theimportanceof factors, also if measured on different scales, or of different types (dichotomous, qualitative or continuous), and permits to compare groups of related factors. In practice theimportanceof prognostic factors often is disappointingly low. From this it follows that even strong and highly significant prognostic factors often do not translate into close determination of individual survival of patients.
ISSN: 0923-7534
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Gynaecological Oncology
× corresponding author
# (joint) last author

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