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Title: Molecular characterization of irinotecan (SN-38) resistant human breast cancer cell lines
Authors: Jandu, Haatisha ×
Aluzaite, Kristina
Fogh, Louise
Thrane, Sebastian Wingaard
Noer, Julie B
Proszek, Joanna
Do, Khoa Nguyen
Hansen, Stine Ninel
Damsgaard, Britt
Nielsen, Signe Lykke
Stougaard, Magnus
Knudsen, Birgitta R
Moreira, José
Hamerlik, Petra
Gajjar, Madhavsai
Smid, Marcel
Martens, John
Foekens, John
Pommier, Yves
Brünner, Nils
Schrohl, Anne-Sofie
Stenvang, Jan #
Issue Date: 22-Jan-2016
Publisher: BioMed Central
Series Title: BMC Cancer vol:16 issue:1 pages:34
Article number: 10.1186/s12885-016-2071-1
Abstract: Studies in taxane and/or anthracycline refractory metastatic breast cancer (mBC) patients have shown approximately 30 % response rates to irinotecan. Hence, a significant number of patients will experience irinotecan-induced side effects without obtaining any benefit. The aim of this study was to lay the groundwork for development of predictive biomarkers for irinotecan treatment in BC.
URI: 
ISSN: 1471-2407
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Non-KU Leuven Association publications
× corresponding author
# (joint) last author

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