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Title: Global epidemiology of drug resistance after failure of WHO recommended first-line regimens for adult HIV-1 infection: a multicentre retrospective cohort study
Authors: Gregson, John *
Tang, Michele *
Ndembi, Nicaise *
Hamers, Raph *
Rhee, Soo-Yon
Marconi, Vincent C
Diero, Lameck
Brooks, Katherine
Theys, Kristof
Rinke de Wit, Tobias F
Arruda, Monica
Garcia, Frederico
Monge, Huldrych F
Günthard, Christopher J
Kanki, Phyllis J
Kumarasamy, Nagalingeshwaran
Kerschberger, Bernard
Mor, Orna
Charpentier, Charlotte
Todesco, Eva
Rokx, Casper
Gras, Luuk
Halvas, Elias K
Sunpath, Henry
Di Carlo, Domenico
Antinori, Antonio
Andreoni, Massimo
Latini, Alessandra
Mussini, Cristina
Aghokeng, Avelin
Sonnerborg, Anders
Neogi, Ujjwal
Fessel, William J
Agolory, Simon
Yang, Chunfu
Blanco, Jose L
Juma, James M
Smit, Erasmus
Schmidt, Daniel
Watera, Christine
Asio, Juliet
Kirungi, Wilford
Tostevin, Anna
El-Hay, Tal
Clumeck, Nathan
Goedhals, Dominique
van Vuuren, Cloete
Bester, Philip Armand
Sabin, Caroline
Mukui, Irene
Santoro, Maria M
Perno, Carlo F
Hunt, Gillian
Morris, Lynn
Camacho, Ricardo Jorge
de Oliveira, Tulio
Pillay, Deenan
Schulter, Eugene
Murakami-Ogasawara, Akio
Reyes-Terán, Gustavo
Romero, Karla
Avila-Rios, Santiago
Sirivichayakul, Sunee
Ruxrungtham, Kiat
Mekprasan, Suwanna
Dunn, David
Kaleebu, Pontiano
Raizes, Elliot
Kantor, Rami
Shafer, Robert W
Gupta, Ravindra K # ×
Issue Date: May-2016
Publisher: Elsevier Science
Series Title: The Lancet Infectious Diseases vol:16 issue:5
Article number: S1473-3099(15)00536-8
Abstract: Antiretroviral therapy (ART) is crucial for controlling HIV-1 infection through wide-scale treatment as prevention and pre-exposure prophylaxis (PrEP). Potent tenofovir disoproxil fumarate-containing regimens are increasingly used to treat and prevent HIV, although few data exist for frequency and risk factors of acquired drug resistance in regions hardest hit by the HIV pandemic. We aimed to do a global assessment of drug resistance after virological failure with first-line tenofovir-containing ART.
URI: 
ISSN: 1473-3099
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Laboratory of Clinical and Epidemiological Virology (Rega Institute)
* (joint) first author
× corresponding author
# (joint) last author

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