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Title: Simultaneous atomic force microscope and quartz crystal microbalance measurements: Investigation of human plasma fibrinogen adsorption
Authors: Choi, KH
Friedt, Jean-Michel
Frederix, Filip
Campitelli, A
Borghs, Gustaaf #
Issue Date: Aug-2002
Publisher: Amer inst physics
Series Title: Applied Physics Letters vol:81 issue:7 pages:1335-1337
Abstract: We have combined the tapping-mode atomic force microscope (AFM) and quartz crystal microbalance (QCM) for simultaneous investigation of human plasma fibrinogen adsorption on a metallic surface using these two instruments. The AFM images show the surface changes with molecular resolution while the corresponding resonance frequency shift of the QCM provides quantitative adsorbed mass estimates over the whole sensing area. The combination of AFM with QCM allowing the simultaneous measurements with two techniques working at very different scales and probing different properties of the adsorbed layer provides quantitative and qualitative information that can distinguish different protein adsorption mechanisms. (C) 2002 American Institute of Physics.
ISSN: 0003-6951
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Electrical Engineering - miscellaneous
Physics and Astronomy - miscellaneous
# (joint) last author

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