Title: Stretch-induced Ca2+ signalling in vascular smooth muscle cells depends on Ca2+ store segregation
Authors: Gilbert, Guillaume
Ducret, Thomas
Marthan, Roger
Savineau, Jean-Pierre
Quignard, Jean-François # ×
Issue Date: Jul-2014
Publisher: British Medical Association
Series Title: Cardiovascular Research vol:103 issue:2 pages:313-23
Article number: 10.1093/cvr/cvu069
Abstract: Calcium is a key second messenger that can be mobilized from both the extracellular medium and intracellular calcium stores. Pulmonary arterial smooth muscle cells (PASMCs) respond to stretch by a calcium increase, a mechanism enhanced during pulmonary hypertension (PH). We investigated the role of the spatial organization between plasma membrane stretch-activated channels (SACs) and intracellular calcium stores [sarcoplasmic reticulum (SR), mitochondria, and lysosomes) in response to stretch.
ISSN: 0008-6363
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Non-KU Leuven Association publications
× corresponding author
# (joint) last author

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