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Title: Investigation of protein adsorption with simultaneous measurements of atomic force microscope and quartz crystal microbalance
Authors: Choi, KH
Friedt, Jean-Michel
Laureyn, W
Frederix, Filip
Campitelli, A
Borghs, Gustaaf #
Issue Date: Jul-2003
Publisher: A v s amer inst physics
Series Title: Journal of vacuum science & technology b vol:21 issue:4 pages:1433-1436
Abstract: We have combined the tapping-mode atomic force microscope (AFM) and quartz crystal microbalance (QCM) for simultaneous investigation and characterization of protein adsorption on various metallic surfaces using these two instruments. The adsorption of proteins such as human plasma fibrinogen and anti-human immunoglobulin onto the metal or oxide/QCM surface were monitored using both methods at the same time when varying the concentration of proteins. The combination of AFM with QCM allowing the simultaneous measurements with two techniques working at very different scales and probing different properties of the adsorbed layer provides quantitative and qualitative information that can distinguish different protein adsorption behavior. (C) 2003 American Vacuum Society.
ISSN: 1071-1023
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Electrical Engineering - miscellaneous
Physics and Astronomy - miscellaneous
# (joint) last author

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