Title: Associations of Soluble CD14 and Endotoxin with Mortality, Cardiovascular Disease, and Progression of Kidney Disease among Patients with CKD
Authors: Poesen, Ruben ×
Ramezani, Ali
Claes, Kathleen
Augustijns, Patrick
Kuypers, Dirk
Barrows, Ian R
Muralidharan, Jagadeesan
Evenepoel, Pieter
Meijers, Björn
Raj, Dominic S #
Issue Date: Sep-2015
Publisher: American Society of Nephrology
Series Title: Clinical Journal of the American Society of Nephrology vol:10 issue:9 pages:1525-33
Article number: CJN.03100315
Abstract: CD14 plays a key role in the innate immunity as pattern-recognition receptor of endotoxin. Higher levels of soluble CD14 (sCD14) are associated with overall mortality in hemodialysis patients. The influence of kidney function on plasma sCD14 levels and its relationship with adverse outcomes in patients with CKD not yet on dialysis is unknown. This study examines the associations between plasma levels of sCD14 and endotoxin with adverse outcomes in patients with CKD.
ISSN: 1555-9041
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Laboratory of Nephrology
Drug Delivery and Disposition
× corresponding author
# (joint) last author

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