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Title: BAL neutrophilia in azithromycin-treated lung transplant recipients: Clinical significance
Authors: Vandermeulen, Elly ×
Verleden, Stijn
Ruttens, David
Moelants, Eva
Mortier, Anneleen
Somers, Jana
Bellon, Hannelore
Piloni, Davide
Dupont, Lieven
Van Raemdonck, Dirk
Proost, Paul
Schols, Dominique
Vos, Robin
Verleden, Geert
Vanaudenaerde, Bart #
Issue Date: Sep-2015
Publisher: Edward Arnold
Series Title: Transplant Immunology vol:33 issue:1 pages:37-44
Article number: 10.1016/j.trim.2015.07.001
Abstract: Azithromycin decreases airway neutrophilia and can prevent chronic lung allograft dysfunction (CLAD) after lung transplantation (LTx). It also can be used to treat lymphocytic bronchiolitis, as it decreases the submucosal infiltrating IL-17 positive lymphocytes. Some patients, while receiving azithromycin, (re)develop increased airway neutrophilia, which we hypothesize to result in worse outcome and to be regulated by an IL-17-independent mechanism.
URI: 
ISSN: 0966-3274
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Laboratory of Virology and Chemotherapy (Rega Institute)
Pneumology
Laboratory of Molecular Immunology (Rega Institute)
Thoracic Surgery
× corresponding author
# (joint) last author

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