ITEM METADATA RECORD
Title: A Markov model for kinesin
Authors: Maes, Christian ×
van Wieren, MH #
Issue Date: Jul-2003
Publisher: Kluwer academic/plenum publ
Series Title: Journal of statistical physics vol:112 issue:1-2 pages:329-355
Abstract: We investigate the validity of a Markov approach for the motility of kinesin. We show in detail how the various mechanochemical states and reaction rates that are experimentally measured, can be used to create a Markov-chain model. We compare the performance of this model to motility data and we find global similarities in the load and ATP-concentration dependency of speed and mean run length. We also discuss the relation between the experimentally found stalling behavior and thermodynamic expectations. Finally, the Markov chain modelling provides a way to calculate the mean entropy production and the (power) efficiency.
URI: 
ISSN: 0022-4715
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Theoretical Physics Section
× corresponding author
# (joint) last author

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