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Title: Clinical Pharmacokinetics of Voriconazole and Posaconazole in Special Patient Populations
Other Titles: Farmacokinetiek van Voriconazole en Posaconazole in Specifieke Patiëntenpopulaties
Authors: Vanstraelen, Kim
Issue Date: 5-Jun-2015
Table of Contents: List of abbreviations

Chapter 1 Introduction p 1
Chapter 2 Objectives p 32

PART 1 VORICONAZOLE

Chapter 3 Impact of voriconazole therapeutic drug monitoring in daily clinical practice
Submitted p 38


Chapter 4 Pharmacokinetic variability of voriconazole should not preclude its use in critically ill patients
Submitted p 62


Chapter 5 Influence of storage temperature on the dose uniformity of voriconazole powder for oral suspension
Int J Pharm Pharm Sci 2014;6(1): 806-808 p 67


Chapter 6 Protein-binding characteristics of voriconazole determined by high-throughput equilibrium dialysis
J Pharm Sci 2014;103(8): 2565-2570 p 74

Chapter 7 Impact of hypoalbuminemia on voriconazole pharmacokinetics in adult critically ill patients
Antimicrob Agents Chemother 2014; 58(11):6782-6789 p 89

Chapter 8 Key elements in determining voriconazole protein binding characteristics
Ther Drug Monit 2014; epub ahead of print p 107

Chapter 9 Saliva is a promising alternative for plasma monitoring of voriconazole
Clin Pharmacokinet 2015; epub ahead of print p 113


PART 2 POSACONAZOLE

Chapter 10 Impact of mucositis on posaconazole absorption in allogeneic stem cell transplant patients
Submitted p131

Chapter 11 A new prophylactic dosing regimen for posaconazole oral suspension in children based on body surface area
Revisions submitted to Pediatr Infect Dis J p 160


Chapter 12 Discussion & Future perspectives p 177

Chapter 13 Summary p 199

Chapter 14 Samenvatting p 203

Chapter 15 Curriculum vitae p 208

Chapter 16 Dankwoord p 213
ISBN: 9789090290508
Publication status: published
KU Leuven publication type: TH
Appears in Collections:Clinical Pharmacology and Pharmacotherapy
Laboratory of Clinical Bacteriology and Mycology

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