Packaging interventions to increase medication adherence: systematic review and meta-analysis
Conn, Vicki S × Ruppar, Todd M Chan, Keith C Dunbar-Jacob, Jacqueline Pepper, Ginette A De Geest, Sabina #
Clayton-Wray Publications Ltd.
Current Medical Research and Opinion vol:31 issue:1 pages:145-60
Inadequate medication adherence is a widespread problem that contributes to increased chronic disease complications and health care expenditures. Packaging interventions using pill boxes and blister packs have been widely recommended to address the medication adherence issue. This meta-analysis review determined the overall effect of packaging interventions on medication adherence and health outcomes. In addition, we tested whether effects vary depending on intervention, sample, and design characteristics.