Title: Urodynamic changes in mice with experimental autoimmune encephalomyelitis correlate with neurological impairment
Authors: Franken, Jan ×
Gevaert, Thomas
Uvin, Pieter
Wauterickx, K
Boeve, Anne-Cathérine
Rietjens, Roma
Boudes, M
Hendriks, J J A
Hellings, N
Voets, Thomas
De Ridder, Dirk #
Issue Date: Apr-2016
Publisher: Allen R. Liss
Series Title: Neurourology and Urodynamics vol:35 issue:4 pages:450-6
Article number: 10.1002/nau.22742
Abstract: Neurogenic bladder dysfunction is a major issue in Multiple Sclerosis (MS). High intravesical pressure should be treated early. Available therapies are insufficient and there is need for drug development and investigation of pathogenesis. Experimental Autoimmune Encephalomyelitis (EAE) in rodents is a well validated model to study MS. Previous research has shown that these animals develop urinary symptoms. However, from clinical studies, we know that symptoms do not necessarily reflect changes in bladder pressure. This paper aims to provide a complete overview of urodynamic changes in a model for detrusor overactivity in MS.
ISSN: 0733-2467
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Laboratory of Ion Channel Research
Organ Systems (+)
× corresponding author
# (joint) last author

Files in This Item:
File Description Status SizeFormat
Franken_et_al-2015-Neurourology_and_Urodynamics.pdf Published 1872KbAdobe PDFView/Open Request a copy

These files are only available to some KU Leuven Association staff members


All items in Lirias are protected by copyright, with all rights reserved.

© Web of science