Lower placental telomere length may be attributed to maternal residential traffic exposure; a twin study
Bijnens, Esmée × Zeegers, Maurice P Gielen, Marij Kicinski, Michal Hageman, Geja J Pachen, Daniëlle Derom, Catherine Vlietinck, Robert Nawrot, Tim S #
Environment International vol:79 pages:1-7
High variation in telomere length between individuals is already present before birth and is as wide among newborns as in adults. Environmental exposures likely have an impact on this observation, but remain largely unidentified. We hypothesize that placental telomere length in twins is associated with residential traffic exposure, an important environmental source of free radicals that might accelerate aging. Next, we intend to unravel the nature-nurture contribution to placental telomere length by estimating the heritability of placental telomere length.